Introduction to molecular biology

NAME OF THE COURSE Introduction to molecular biology

Code

KTH107

Year of study

1.

Course teacher

Assoc Prof Olivera Politeo

Credits (ECTS)

5.0

Associate teachers

Prof Tatjana Zemunik

Type of instruction (number of hours)

P S V T

30

15

15

0

Status of the course

Mandatory

Percentage of application of e-learning

0 %

COURSE DESCRIPTION

Course objectives

Acquisition of basic knowledge and skills in the field of molecular biology.

Course enrolment requirements and entry competences required for the course

 

Learning outcomes expected at the level of the course (4 to 10 learning outcomes)

- Explain the structure of cells and the role of various cellular structures.
- Understanding the structure and role of chromosomal structures.
- Explain and understan the principle, the importance and mechanisms of DNA replication.
- Explain and understan the principle, the importance and mechanisms of transcription.
- Explain and understan the principle, the importance and mechanisms of translation.
- Understand the basic concepts and principles of recombinant technology.
- To know and learn the basic methods and techniques of molecular biology.

Course content broken down in detail by weekly class schedule (syllabus)

LECTURES:
Introduction to molecular biology. Procaryotic and eucaryotic cell. (3) The structure and function of cells. Cell divisions. (3) The model organisms. (1) Nucleotids and nucleic acids. (1) The DNA organization into chromosomes. (1) DNA identification as the genetic material. (1) DNA replication. (2) DNA repair. (1) DNA recombination. (1) Telomeres. (1) Transcription. RNA processing. (2) Translation (2) Regulation of genes expression. (1) Glycosylation in the ER and Golgi Complex. (2) Folding and processing of proteins (2) Genetic engineering: Restriction endonuclease. Vectors. Cloning. (2) The basic methods and techniques of molecular biology. (2) Molecular medicine. Cancer. (2)
SEMINARS:
The life cycle of cells. (1) Mendel’s laws. (1) DNA replication. (1) Transcription. (1) Translation. (1) Genomes. (1) Prions and prion diseases. (1) Genetically modified organisms. (1) Gene therapy (1) Cancer. (1)
EXERCISES:
DNA isolation. PCR. DNA electrophoresis.

Format of instruction:

Student responsibilities

 

Screening student work (name the proportion of ECTS credits for eachactivity so that the total number of ECTS credits is equal to the ECTS value of the course):

Class attendance

0.0

Research

0.0

Practical training

0.0

Experimental work

1.0

Report

0.0

 

 

Essay

0.0

Seminar essay

1.0

 

 

Tests

0.0

Oral exam

1.0

 

 

Written exam

2.0

Project

0.0

 

 

Grading and evaluating student work in class and at the final exam

Activity during attendance, presentation of seminar papers, experimental work and final exam.

Required literature (available in the library and via other media)

Title

Number of copies in the library

Availability via other media

G. M. Cooper, R. E. Hausman. Stanica. 5.izdanje. 2010.

0

Optional literature (at the time of submission of study programme proposal)

B. Lewin. Genes IX. 2008.
G. M. Malacinski. Essentials of Molecular Biology. Forth Edition, 2003.
Lodish, Berg, Zipursky, Matsudaria, Batimore, Darnell. Molecular Cell Biology. Forth Edition, 2000

Quality assurance methods that ensure the acquisition of exit competences

Quality assurance will be performed at three levels:
(1) University Level;
(2) Faculty Level by Quality Control Committee;
(3) Lecturer’s Level.

Other (as the proposer wishes to add)