| NAME OF THE COURSE |
Basic Biotechnology |
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Code |
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Course teacher |
Prof Branka Andričić |
Credits (ECTS) |
3.0 |
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Associate teachers |
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Type of instruction (number of hours) |
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Status of the course |
Mandatory |
Percentage of application of e-learning |
0 % |
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| COURSE DESCRIPTION |
Course objectives |
Gaining of basic theoretical knowledge in biotechnology as well as the role and application of microorganisms and enzymes in different areas. |
Course enrolment requirements and entry competences required for the course |
Biochemistry - enrolled. |
Learning outcomes expected at the level of the course (4 to 10 learning outcomes) |
- definition of term biotechnology
- differentiate the primary and secondary cell metabolism and its application in biotechnology
- explain of microbe cell growth diagram
- explain the advantages of isolated enzymes in biotechnology
- describe of basic bioreactor design
- describe the basic methods of intracellular products isolation
- outline some examples of biotechnological processes. |
Course content broken down in detail by weekly class schedule (syllabus) |
1st week: Description and overview of the course. Definitions of biotechnology, interdisciplinary of the field, history development, application areas.
2nd week: Perception of biotechnology in society. Metabolism and control of metabolic processes; primary and secondary metabolism, substrates.
3rd week: Anaerobic and aerobic metabolism. Microorganisms in biotechnology (bacterial, fungi (yeasts and moulds). Microbial growth kinetics. Determination of specific growth rate and Monod constant.
4th week: Enzyme technology (enzyme characteristics as the biocatalysts, advantages and disadvantages compared to whole cells). Enzyme kinetics.
5th week: Enzyme sources. Selection, production and immobilization of enzymes.
6th week: Biocatalysts in non-conventional processes. Bioreactors, photo-bioreactors, design.
7th week: Oxygen transfer and oxygen concentration determination. Heat transfer in bioreactor. An overview of the previous lecture for the test.
First test.
8th week: Extracellular, periplasmic and extracellular products of metabolism. Down-stream processing: separation solid-liquid, isolation of intracellular products.
9th week: Concentration and purification of products from bioreactor. Purification process control.
10th week: Process economy: cost estimation and an example of process design. An overview of biotechnological processes – basic scheme of biotechnological process.
11th week: Alcohol fermentation and its application in industry.
12th week: Lactic acid fermentation and its application in industry. Anaerobic biomass fermentation.
13th week: Biotechnology in pharmacy. Bacterial polymers.
14th week: Biotechnology in environmental protection and waste water treatment. Biosensors.
15th week: An overview of the previous lecture for the test. Second test. |
Format of instruction: |
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Student responsibilities |
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Screening student work (name the proportion of ECTS credits for eachactivity so that the total number of ECTS credits is equal to the ECTS value of the course): |
Class attendance |
1.0 |
Research |
0.0 |
Practical training |
0.0 |
Experimental work |
0.0 |
Report |
0.0 |
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Essay |
0.0 |
Seminar essay |
0.0 |
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Tests |
0.8 |
Oral exam |
0.6 |
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Written exam |
0.6 |
Project |
0.0 |
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Grading and evaluating student work in class and at the final exam |
The complete exam can be passed through two tests during semester. The passing score is 60 % and the fraction of each test is 45%. Attendance on lectures (80-100%) is further 10% of final grade. In the exam period the student has to attend to written and oral exam (passing score is 60%). Previous activity (one passed test) is valid in summer exam period with fraction of 10%. Written exam is 40% and oral exam is 50%. Students without any successful previous activity attend to written and oral exam (passing score is 60%) both with fraction of 50%.
Grades: successful (60% – 70%), good (71% – 80%), very good (81% – 90%), excellent (91% – 100%). |
Required literature (available in the library and via other media) |
Title |
Number of copies in the library |
Availability via other media |
C. Ratlege, B. Kristiansen, Eds. Basic Biotechnology, Cambridge University Press, Cambridge, 2006. |
1 |
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Optional literature (at the time of submission of study programme proposal) |
J.E. Smith, Biotechnology, Cambridge University Press, Cambridge, 2000.
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Quality assurance methods that ensure the acquisition of exit competences |
Quality of the teaching and learning, monitored at the level of the (1) teachers, accepting suggestions of students and colleagues, and (2) faculty, conducting surveys of students on teaching quality. |
Other (as the proposer wishes to add) |
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