Chemistry in pharmacology

NAME OF THE COURSE Chemistry in pharmacology

Code

KTG319

Year of study

3.

Course teacher

Assoc Prof Marija Bralić

Credits (ECTS)

4.0

Associate teachers

Mislav Šolić

Type of instruction (number of hours)

P S V T

30

15

0

0

Status of the course

Elective

Percentage of application of e-learning

0 %

COURSE DESCRIPTION

Course objectives

Introducing chemical characteristics of drug substances. Basic divisions and characteristics of certain classes of drugs.

Course enrolment requirements and entry competences required for the course

Enrolled in or passed the course Exercise of chemistry in pharmacology

Learning outcomes expected at the level of the course (4 to 10 learning outcomes)

After course students will be able to :
1. definition of basic concepts and distribution of certain classes of drugs
2. physicochemical properties of drugs
3. effect and mechanism of drugs
4. Development and mode of action of drugs
5. adverse effects of drugs and their resistance
6. interactions with other drugs

Course content broken down in detail by weekly class schedule (syllabus)

Lecture 1: Introduction: definition and application
Lecture 2: Chemical structures and stereochemical characteristics of drug substances
Lecture 3: Chemical structures and stereochemical characteristics of drug substances
Seminar 1 (2 hours): Introduction to the legislation of drugs
Lecture 4: Physico-chemical properties of drugs
Seminar 2 (2 hours): Distribution of drugs by pharmacological groups
Lecture 5: Physico-chemical properties of drugs
Seminar 3 (2 hours): The pharmacokinetics of drugs
Lecture 6: Chemical stability and incompatibility drugs
Lecture 7: Chemical stability and incompatibility drugs
Lecture 8: Activity and mechanism of action
Seminar 4 (2 hours ): The pharmacodynamics of drugs
Lecture 9:. Division according pharmacological groups
Seminar 5 (2 hours): analgesics
Lecture 10: The properties of certain classes of drugs
Seminar 6 (2 hours): anxiolytics
Lecture 11: Development and explanation of drug action
Seminar 7 (2 hours): antibiotics
Lecture 12: The main stages of drug action: absorption, distribution, metabolic processes, removal
Lecture 13: The main stages of drug action: absorption, distribution, metabolic processes, removal
Lecture 14: Introduction to side effects, resistance, interactions with other drugs
Lecture 15: Introduction to side effects, resistance, interactions with other drugs
Seminar 8 (1 hour): Minerals in pharmaceuticals, Chromatography and detection of drugs

Format of instruction:

Student responsibilities

 

Screening student work (name the proportion of ECTS credits for eachactivity so that the total number of ECTS credits is equal to the ECTS value of the course):

Class attendance

0.5

Research

0.0

Practical training

0.0

Experimental work

0.0

Report

0.0

 

 

Essay

0.0

Seminar essay

0.5

 

 

Tests

1.0

Oral exam

1.0

 

 

Written exam

1.0

Project

0.0

 

 

Grading and evaluating student work in class and at the final exam

During the semester, the two partial tests to check if the knowledge of students from courses included material. During the semester students will be selected from the lecture topic to make a seminar that will affect the final grade. After completion of the semester, students take a written exam courses included material from the seminar. If the student meets at one of the partial tests during the semester, material from passing the test does not need to take the written exam. After passing the written part of the exam, the oral exam. For all aspects of teaching evaluation will be conducted according to the following criteria: <55% inadequate; 55% -65% is sufficient; 66% -75% good; 76% -85% very good;> 86% excellent. The final grade will be the arithmetic average of ratings from exercises, written assessment and oral examination.

Required literature (available in the library and via other media)

Title

Number of copies in the library

Availability via other media

J.B. Stenlake, Foundations of Molecular Pharmacology: Chemical Basis of Drug Action, 1979

0

U Zavodu 1 primjerak

K.A. Connors, Chemical Stability of Pharmaceuticals: A Handbook for Pharmacists, 1986.

0

U Zavodu 1 primjerak

Kent and Riegel’s, Handbook of industrial chemistry and biotechnology, Volume I, Springer Science+Business Media, LLC, 2007.

0

U Zavodu 1 primjerak

Eiichiro Ochiai, Chemicals for Life and Living, Springer-Verlag Berlin Heidelberg 2011

0

U Zavodu 1 primjerak

Optional literature (at the time of submission of study programme proposal)

T.C. Marrs, R.L. Maynard, F.R. Sidell, Chemical Warfare Agents: Toxicology and Treatment, 1996;
L. Poller, Oral Anticoagulants: Chemical and Biological Preperties and Clinical Applications, 1996.

Quality assurance methods that ensure the acquisition of exit competences

Methods Quality assurance will be performed at three levels: (1) University; (2) Faculty Level by Quality Control Committee of teaching; (3) Level.

Other (as the proposer wishes to add)